Fibroid Medical Therapy

First line treatment may involve oral contraceptive pills, either combination pills or progestin-only, in an effort to manage symptoms.

If unsuccessful, further medical therapy involves the use of medication to reduce estrogens in an attempt to create a medical menopause-like situation.

Gonadotropin-releasing hormone analogs are used for this. GNRH analogs, however, are short term treatments only. Selective progesterone receptor modulators, such as Progenta, were under investigation in 2005, because their use as therapeutic agents was desired.